Dietary docosahexaenoic and eicosapentaenoic acid: Emerging mediators of inflammation

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Dietary intake of eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) in children - a workshop report.

There is controversy whether children should have a dietary supply of preformed long-chain polyunsaturated n-3 fatty acids EPA and DHA. The aims of the workshop were to review evidence for a possible benefit of a preformed EPA and/or DHA supply, of data required to set desirable intakes for children aged 2-12 years, and of research priorities. The authors concluded that EPA and DHA intakes per ...

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Effects of dietary treatment of rats with eicosapentaenoic acid or docosahexaenoic acid on hepatic lipid metabolism.

(1) Effects of dietary treatment of male albino rats with eicosapentaenoic acid (EPA) or docosahexaenoic acid on hepatic mitochondrial lipid metabolism have been investigated. (2) Mitochondria isolated from rats given these treatments were shown to have increased ability to respire on acyl-CoA esters in the presence of malonate. This effect was expressed with most of the long-chain acyl-CoA est...

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Dietary eicosapentaenoic acid and docosahexaenoic acid from fish oil. Their incorporation into advanced human atherosclerotic plaques.

The incorporation of fatty acids from dietary fish oil was measured in obstructive atherosclerotic plaques removed from 11 patients fed fish oil, rich in omega-3 fatty acids, for 6-120 days before a planned arterial endarterectomy. The fatty acids of plasma and atheroma were analyzed with special reference to docosahexaenoic acid (DHA, 22:6) and eicosapentaenoic acid (EPA, 20:5), the principal ...

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Eicosapentaenoic acid and docosahexaenoic acid moderate inflammation in porcine cartilage explants

Objective: To characterize the effects of eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) and arachidonic acid (ARA) in various combinations on indices of inflammation in recombinant porcine IL-1 beta stimulated porcine articular cartilage explants. Methods: Cartilage was obtained from the humeral-ulnar joints of Yorkshire x Landrace market sized gilts. Explants were harvested from t...

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Effect of eicosapentaenoic and docosahexaenoic acid on resting and exercise-induced inflammation and oxidative stress

Methods 14 men (26 ± 5 yrs) supplemented with 2224 mg EPA (MorEPA Mini; Minami Nutrition, Belgium)+2208 mg DHA (MorDHA Mini; Minami Nutrition, Belgium) and a placebo for 6 weeks using a random order, double blind cross-over design (with an 8 week washout period) prior to performing a 60 minute treadmill climb using a weighted backpack. Blood was collected before and at 0, 0.5, 24, and 48 hours ...

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ژورنال

عنوان ژورنال: Prostaglandins, Leukotrienes and Essential Fatty Acids

سال: 2009

ISSN: 0952-3278

DOI: 10.1016/j.plefa.2009.05.010